abstract：OBJECTIVES:We sought to assess large bowel motility, induced by 2 prokinetic agents, senna tea and erythromycin, using functional cine magnetic resonance imaging (MRI). MATERIALS AND METHODS:Twelve volunteers underwent functional cine MRI before and after the administration of senna tea or erythromycin. The protocol c...

journal_title：Investigative radiology

authors： Buhmann S,Kirchhoff C,Wielage C,Mussack T,Reiser MF,Lienemann A

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:The aim of this work was to quantitatively evaluate the pharmacokinetic pattern of Gd-EOB-DTPA in a model of isolated and perfused mouse liver by using magnetic resonance imaging (MRI) and monochromatic quantitative computed tomography (MQCT). MATERIALS AND METHODS:For MQCT, perfusions were realized with th...

journal_title：Investigative radiology

authors： Segers J,Le Duc G,Laumonier C,Troprès I,Elst LV,Muller RN

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the extent to which various commercially available gadolinium-containing contrast-enhancing (CE) agents can interfere with the measurement of calcium levels by currently used laboratory methods, suggesting (spurious) hypocalcemia or hypercalcemia with a potential ris...

journal_title：Investigative radiology

authors： Löwe A,Balzer T,Hirt U

更新日期：2005-08-01 00:00:00

abstract：PURPOSE:We sought to evaluate the potential of dynamic contrast enhancement after the intravenous administration of an iodine-based contrast medium in full-field digital mammography. MATERIAL AND METHODS:A protocol for image acquisition was established for contrast-enhanced mammography and the mammography unit (Senogr...

journal_title：Investigative radiology

authors： Diekmann F,Diekmann S,Jeunehomme F,Muller S,Hamm B,Bick U

更新日期：2005-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:The purpose of this study was to investigate the feasibility, efficacy, and safety of ultrasound-guided percutaneous cryotherapy of stage T1 breast cancers. MATERIALS AND METHODS:Thirty patients with biopsy-confirmed breast cancers with tumor diameters of 15 mm or smaller (range, 5-15 mm; media...

journal_title：Investigative radiology

authors： Pfleiderer SO,Marx C,Camara O,Gajda M,Kaiser WA

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement. MATERIALS AND METHODS:One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field...

journal_title：Investigative radiology

authors： Riedl CC,Jaromi S,Floery D,Pfarl G,Fuchsjaeger MH,Helbich TH

更新日期：2005-06-01 00:00:00

abstract：PURPOSE:We sought to develop a robotic system for computed tomography (CT)-guided biopsy to validate the feasibility, accuracy, and efficacy of the system using phantom tests. MATERIALS AND METHODS:Ten peas (mean diameter 9.9+/-0.4 mm) embedded within a gel phantom were selected for biopsy. Once the best access was de...

journal_title：Investigative radiology

authors： Kettenbach J,Kronreif G,Figl M,Fürst M,Birkfellner W,Hanel R,Ptacek W,Bergmann H

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:Multidetector-row computed tomography coronary images are usually analyzed in mid-diastole (MD). Because of slow coronary motion also in end-systole (ES), we evaluated the impact on image quality of including ES images and defined an efficient reconstruction protocol. MATERIAL AND METHODS:In 50 coronary mul...

journal_title：Investigative radiology

authors： Sanz J,Rius T,Kuschnir P,Fuster V,Goldberg J,Ye XY,Wisdom P,Poon M

更新日期：2005-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The effect of breathholding on pulmonary perfusion remains largely unknown. The aim of this study was to assess the effect of inspiratory and expiratory breathhold on pulmonary perfusion using quantitative pulmonary perfusion magnetic resonance imaging (MRI). METHODS AND RESULTS:Nine healthy v...

journal_title：Investigative radiology

authors： Fink C,Ley S,Risse F,Eichinger M,Zaporozhan J,Buhmann R,Puderbach M,Plathow C,Kauczor HU

更新日期：2005-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To investigate the capacity of manganese dipyridoxyl diphosphate (MnDPDP)-enhanced magnetic resonance imaging (MRI) to discriminate the injured myocardium from the normal myocardium in a cat model. MATERIALS AND METHODS:Fourteen cats were prepared for acute myocardial infarction with 90-minute...

journal_title：Investigative radiology

authors： Kim TH,Yang DH,Choi JW,Kim ST,Yoon JH,Shin JH,Seo JB,Gong GY,Lim TH

更新日期：2005-01-01 00:00:00

abstract：:Surgical resection is the standard of care for colorectal metastases isolated to the liver. However, only 10-25% of the patients are eligible for resection because of extent and location of the disease in the liver or concurrent medical conditions. Image-guided radiofrequency (RF) ablation is a minimally invasive tech...

journal_title：Investigative radiology

authors： Lencioni R,Crocetti L,Cioni D,Della Pina C,Bartolozzi C

更新日期：2004-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...

journal_title：Investigative radiology

authors： Hamer OW,Völk M,Zorger N,Borisch I,Büttner R,Feuerbach S,Strotzer M

更新日期：2004-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The aim of the study was to determine optimal thresholds for semiquantitative perfusion parameters and to evaluate the influence of different segmentation models in detecting malperfused regions. MATERIAL AND METHODS:In 6 healthy subjects and 13 patients with coronary artery disease, contrast-...

journal_title：Investigative radiology

authors： Fenchel M,Kramer U,Helber U,Stauder NI,Franow A,Claussen CD,Miller S

更新日期：2004-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare trabecular bone structure measures obtained in magnetic resonance images of the distal radius and the calcaneus as well as computed tomographic images of the spine versus bone mineral density (BMD) of the spine and the calcaneus in the prediction of osteoporotic spine fracture status...

journal_title：Investigative radiology

authors： Link TM,Bauer J,Kollstedt A,Stumpf I,Hudelmaier M,Settles M,Majumdar S,Lochmüller EM,Eckstein F

更新日期：2004-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the safety and pharmacokinetics of a newly developed MR contrast medium consisting of very small superparamagnetic iron oxide particles (VSOP) coated with citrate (VSOP-C184) in a clinical phase I trial. METHODS:A total of 18 healthy subjects received either VSOP-C184 (core diamete...

journal_title：Investigative radiology

authors： Taupitz M,Wagner S,Schnorr J,Kravec I,Pilgrimm H,Bergmann-Fritsch H,Hamm B

更新日期：2004-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Our purpose was to validate contrast-enhanced computed tomography (CECT)-derived quantitative measures of perfusion and permeability against gold standard techniques of fluorescent microspheres and Evan's Blue dye, respectively. MATERIALS AND METHODS:Normal and tumor-bearing (R3230AC) Fischer ...

journal_title：Investigative radiology

authors： Pollard RE,Garcia TC,Stieger SM,Ferrara KW,Sadlowski AR,Wisner ER

更新日期：2004-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To test noninvasive inductive heating of implanted vascular stents as an alternative approach for reduction or prevention of neointimal hyperplasia. METHODS:Calorimetric pretests were performed to get an orientation on the different parameters of influence for inductive heating of stents. The ...

journal_title：Investigative radiology

authors： Floren MG,Günther RW,Schmitz-Rode T

更新日期：2004-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Paclitaxel added to angiographic contrast medium (CM) has been shown to inhibit restenosis in the porcine coronary overstretch model. This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations. MATERIALS AND METHODS:Fifteen p...

journal_title：Investigative radiology

authors： Speck U,Scheller B,Abramjuk C,Grossmann S,Mahnkopf D,Simon O

更新日期：2004-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To assess the influence of injection rates and volumes on the arrival time of contrast material (CM) in the common carotid artery, the jugular vein and the resulting arterial-venous transit time. Additionally the relationship between injection parameters and the extent of a CM plateau was evalu...

journal_title：Investigative radiology

authors： Herold T,Paetzel C,Völk M,Bachthaler M,Zorger N,Feuerbach S,Strotzer M,Lenhart M

更新日期：2004-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a new animal model for the evaluation of the renal tolerance of contrast agent and its application to diatrizoate and iotrolan injections in comparison to saline and mannitol solution. MATERIALS AND METHODS:The nephrotoxic potential of intravenously injected contrast agents in Beagl...

journal_title：Investigative radiology

authors： Krause W,Gilles T

更新日期：2003-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study was to determine whether cerebral fat embolism demonstrated reversible or irreversible findings in magnetic resonance (MR) imaging over time and to compare the features in MR images with histologic findings in a cat model. MATERIALS AND METHODS:MR images were obtained...

journal_title：Investigative radiology

authors： Kim HJ,Lee CH,Lee SH,Moon TY

更新日期：2003-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:In contrast-enhanced dual-energy subtraction imaging 2 images acquired postcontrast media administration at different energies are subtracted to highlight structures hidden in the absence of contrast media. X-ray spectra of the newly developed digital full-field mammography units (GE Senographe...

journal_title：Investigative radiology

authors： Lawaczeck R,Diekmann F,Diekmann S,Hamm B,Bick U,Press WR,Schirmer H,Schön K,Weinmann HJ

更新日期：2003-09-01 00:00:00

abstract：INTRODUCTION:The aim of the present study was to evaluate the potential of high-resolution MRI at 2 Tesla (T) for direct noninvasive imaging of the aortic wall in a mouse model of atherosclerosis. MATERIAL AND METHODS:A specific mouse antenna was developed and sequence parameters were adjusted. T(1)- and T2-weighted i...

journal_title：Investigative radiology

authors： Chaabane L,Soulas EC,Contard F,Salah A,Guerrier D,Briguet A,Douek P

更新日期：2003-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:We investigated whether it is possible to investigate degenerative changes in human tissue on a sub-100-microm resolution scale not only on special high-field small-bore MR-microscopy systems but also on a 3T whole-body MR-scanner. METHODS:Spin-spin relaxation, proton density, and diffusion mi...

journal_title：Investigative radiology

authors： Berg A,Sailer J,Rand T,Moser E

更新日期：2003-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a simple and robust helium3 polarization system dedicated to small animal imaging. To demonstrate the potential of helium3 imaging for pulmonary ventilation and perfusion studies. METHODS:A home-built polarization system based on spin-exchange technique was used. This system was app...

journal_title：Investigative radiology

authors： Stupar V,Berthezène Y,Canet E,Tournier H,Dupuich D,Crémillieux Y

更新日期：2003-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:To estimate the sensitivity to find small coronary artery calcium lesions with use of different slice widths with electron beam tomography. MATERIALS AND METHODS:Two studies were performed. Study 1 utilized double scanning of a stationary cork phantom with three different slice thickness (1.5, ...

journal_title：Investigative radiology

authors： Mao S,Child J,Carson S,Liu SC,Oudiz RJ,Budoff MJ

更新日期：2003-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The capability of an indirect computed tomographic lymphography (CT-LG) using a nonionic monometric contrast medium iopamidol for visualizing breast lymphatic pathways was preliminarily tested. MATERIALS AND METHODS:In 10 female dogs, a total of 0.5 and 1 mL of undiluted iopamidol was injected...

journal_title：Investigative radiology

authors： Suga K,Ogasawara N,Yuan Y,Okada M,Matsunaga N,Tangoku A

更新日期：2003-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The objective of the present study was to compare the data regarding the ability of real-time myocardial contrast echocardiography (MCE) to assess altered myocardial blood flow produced by graded coronary stenoses between open- and closed-chest canine models. MATERIALS AND METHODS:Three grades...

journal_title：Investigative radiology

authors： Masugata H,Peters B,Lafitte S,Yao B,Strachan M,Ling Kwan O,Ohmori K,Mizushige K,Kohno M

更新日期：2003-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the changes in the microbubble population of a currently available ultrasound contrast agent (USCA) through attenuation measurements to optimize its clinical use. MATERIALS AND METHODS:The microbubble population from a galactose-based USCA (Levovist, Schering AG, Germany) was chara...

journal_title：Investigative radiology

authors： Correas JM,Kurtisovski E,Bridal SL,Amararene A,Hélénon O,Berger G

更新日期：2002-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:New targeted microbubbles directed to the GPIIb IIIa receptor have been developed. The objective was to determine whether targeting microbubbles to clots would enhance ultrasound imaging. Systematic studies were designed to determine whether in vitro methodology is an acceptable predictor of in...

journal_title：Investigative radiology

authors： Schumann PA,Christiansen JP,Quigley RM,McCreery TP,Sweitzer RH,Unger EC,Lindner JR,Matsunaga TO

更新日期：2002-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The vasoconstriction of the renal arteries is frequently considered as a crucial factor for radiocontrast-induced nephropathy. A direct effect of iodinated radiographic contrast medium (RCM) on vascular smooth muscle is supposed to be one component of the vascular response. We studied the effec...

journal_title：Investigative radiology

authors： Uder M,Humke U,Pahl M,Jansen A,Utz J,Kramann B

更新日期：2002-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare electron beam tomography (EBT) with MR imaging (MRI) for detection of restenosis after coronary angioplasty (PTCA). METHODS:One hundred eighteen patients after PTCA were investigated. By EBT, 50 axial images were acquired (3-mm slice thickness, 120-160 mL radiographic contrast agent...

journal_title：Investigative radiology

authors： Ropers D,Regenfus M,Stilianakis N,Birke S,Kessler W,Moshage W,Laub G,Daniel WG,Achenbach S

更新日期：2002-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Gray scale and power Doppler sonography are commonly used to evaluate cervical lymph nodes. This study was undertaken to identify which of the features used in ultrasound of cervical lymph nodes is readily applicable in routine clinical practice. METHODS:Two hundred and eight-six patients diag...

journal_title：Investigative radiology

authors： Ahuja A,Ying M

更新日期：2002-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The aim of the study was to examine the effects of azelastine on proliferation, clonogenic activity, cell-cycle, and migration of human aortic smooth-muscle cells (haSMCs) in vitro. METHODS:HaSMCs were treated for 4 days with azelastine (1 micromol/L, 25 micromol/L, 50 micromol/L). Half of the...

journal_title：Investigative radiology

authors： Schöber W,Wiskirchen J,Kehlbach R,Gebert R,Rodegerdts E,Betsch A,Johst U,Feuls R,Claussen CD,Duda SD

更新日期：2002-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Dynamic contrast enhanced (DCE) MR mammography (MRM) uses tumor capillary density differences for prognosis. The heterogeneous response of permeability-surface area products (PS = Kp<-->t) was examined in mammary tumors, as a function of contrast agent size, to determine what effect ROI size mi...

journal_title：Investigative radiology

authors： Aref M,Brechbiel M,Wiener EC

更新日期：2002-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare the diagnostic efficacy of a standard dose of MRI contrast agent in the evaluation of primary brain tumors and metastases using a high-field 3 tesla MR unit versus a 1.5 tesla MR unit. METHODS:Sixteen patients with brain tumors were examined at both field strengths using identical a...

journal_title：Investigative radiology

authors： Nöbauer-Huhmann IM,Ba-Ssalamah A,Mlynarik V,Barth M,Schöggl A,Heimberger K,Matula C,Fog A,Kaider A,Trattnig S

更新日期：2002-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a computer-assisted analysis of complex joint motion based on standard fluoroscopic sequences. MATERIALS AND METHODS:Fluoroscopic sequences of 10 normal shoulders and 20 patients after total shoulder arthroplasty were recorded during abduction and adduction. The analysis of the shou...

journal_title：Investigative radiology

authors： Pfirrmann CW,Huser M,Székely G,Hodler J,Gerber C

更新日期：2002-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The objective is to assess the diagnostic accuracy and interobserver variability of multiphase 3D gadolinium-enhanced magnetic resonance angiography (3D-Gd-MRA) for assessment of abdominal and pelvic vascular disease. METHODS:In 41 patients from two different institutions multiphase 3D-Gd-MRA ...

journal_title：Investigative radiology

authors： Schoenberg SO,Essig M,Hallscheidt P,Sharafuddin MJ,Stolpen AH,Knopp MV,Yuh WT

更新日期：2002-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the imaging characteristics of various iliac artery stents and stent-grafts in a multislice, computed tomography angiography (MSCTA) phantom study. METHODS:Twelve types of stents and three stent-grafts made of different materials (steel, nitinol, tantalum, cobalt-based alloy) were ...

journal_title：Investigative radiology

authors： Maintz D,Fischbach R,Juergens KU,Allkemper T,Wessling J,Heindel W

更新日期：2001-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare gadobenate dimeglumine (Gd-BOPTA) with gadopentetate dimeglumine (Gd-DTPA) for magnetic resonance imaging of the liver. METHODS:The contrast agent Gd-BOPTA or Gd-DTPA was administered at a dose of 0.1 mmol/kg to 257 patients suspected of having malignant liver tumors. Dynamic phase ...

journal_title：Investigative radiology

authors： Kuwatsuru R,Kadoya M,Ohtomo K,Tanimoto A,Hirohashi S,Murakami T,Tanaka Y,Yoshikawa K,Katayama H

更新日期：2001-11-01 00:00:00